Affiliation:
1. Medical Research Council Clinical Research Center, Harvard Hospital, Salisbury, England
Abstract
Erythrocytes and H-HeLa cells were treated with neuraminidase and then compared with untreated cells for their ability to adsorb to mycoplasma colonies or be agglutinated by suspensions of the mycoplasmas. Of the 17 mycoplasma serotypes examined, only 4 were found to use neuraminic acid receptors; these were
Mycoplasma pneumoniae, M. gallisepticum, M. synoviae
, and mycoplasma WR1. Not all strains of a serotype behaved alike. Thus, removal of receptors on erythrocytes for one strain of
M. gallisepticum
required at least 100 times the concentration of neuraminidase needed to remove them for another strain. The mechanism of attachment of erythrocytes to mycoplasma colonies does not appear to be the same as that for attachment to mycoplasmas in suspension.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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