Affiliation:
1. Department of Food Animal and Equine Medicine, North Carolina State University College of Veterinary Medicine, Raleigh 27606, USA.
Abstract
Equine infectious anemia virus is a lentivirus that replicates in mature tissue macrophages of horses. Ponies were infected with equine infectious anemia virus. During febrile episodes, proviral DNA was detectable, but viral mRNA was not detectable. As cultured blood monocytes from these ponies differentiated into macrophages, viral expression was upregulated. In situ hybridization confirmed that viral transcription occurred in mature macrophages.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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