The reovirus nonstructural protein sigma1NS is recognized by murine cytotoxic T lymphocytes-Reference-Cited by-同舟云学术

The reovirus nonstructural protein sigma1NS is recognized by murine cytotoxic T lymphocytes

Published:1996-11 Issue:11 Volume:70 Page:8160-8164
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Hoffman L M¹,Hogan K T¹,Cashdollar L W¹

Affiliation:

1. Department of Microbiology, Medical College of Wisconsin, Milwaukee 53226, USA.

Abstract

The cytotoxic T-lymphocyte (CTL) response in reovirus-infected C3H mice was investigated by using reovirus-vaccinia virus recombinants. Results of cytotoxicity assays indicated that the nonstructural protein sigma1NS elicited a significant CTL response. Experiments with sigma1NS-specific CTL lines showed that both strain-specific and cross-reactive epitopes exist in the sigma1NS protein.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.70.11.8160-8164.1996

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