Wide Distribution of Closely Related, Antibiotic-Producing Arthrobacter Strains throughout the Arctic Ocean

Author:

Wietz Matthias1,Månsson Maria2,Bowman Jeff S.3,Blom Nikolaj4,Ng Yin1,Gram Lone1

Affiliation:

1. National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark

2. Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark

3. School of Oceanography and Astrobiology Program, University of Washington, Seattle, Washington, USA

4. Novo Nordisk Foundation Center for Biosustainability & Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark

Abstract

ABSTRACT We isolated 16 antibiotic-producing bacterial strains throughout the central Arctic Ocean, including seven Arthrobacter spp. with almost identical 16S rRNA gene sequences. These strains were numerically rare, as revealed using 454 pyrosequencing libraries. Arthrobacter spp. produced arthrobacilins A to C under different culture conditions, but other, unidentified compounds likely contributed to their antibiotic activity.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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