Can Levofloxacin Be a Useful Alternative to Trimethoprim-Sulfamethoxazole for Treating Stenotrophomonas maltophilia Bacteremia?

Author:

Cho Sun Young,Kang Cheol-In,Kim Jungok,Ha Young Eun,Chung Doo Ryeon,Lee Nam Yong,Peck Kyong Ran,Song Jae-Hoon

Abstract

ABSTRACTA retrospective study was conducted to evaluate the efficacy of levofloxacin in the treatment ofStenotrophomonas maltophiliabacteremia. The 30-day mortality rates were similar between the trimerthoprim-sulfamethoxazole (TMP-SMX) and levofloxacin treatment groups. Adverse events related to antibiotics occurred more frequently in patients receiving TMP-SMX, and recurrent bacteremia due to levofloxacin-resistantS. maltophiliastrains developed in patients treated with levofloxacin. Our data suggest that levofloxacin can be a useful alternative option for treatingS. maltophiliainfections.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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