Performance of the MGIT TBc Identification Test and Meta-Analysis of MPT64 Assays for Identification of the Mycobacterium tuberculosis Complex in Liquid Culture-Reference-Cited by-同舟云学术

Performance of the MGIT TBc Identification Test and Meta-Analysis of MPT64 Assays for Identification of the Mycobacterium tuberculosis Complex in Liquid Culture

Published:2011-12 Issue:12 Volume:49 Page:4343-4346
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Brent Andrew J.¹²,Mugo Daisy¹,Musyimi Robert¹,Mutiso Agnes¹,Morpeth Susan¹³,Levin Michael⁴,Scott J. Anthony G.¹³

Affiliation:

1. KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya

2. Wellcome Trust Centre for Clinical Tropical Medicine, Imperial College London, London, United Kingdom

3. Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

4. Department of Pediatrics, Imperial College London, London, United Kingdom

Abstract

ABSTRACT Rapid MPT64-based immunochromatographic tests (MPT64 ICTs) have been developed to detect Mycobacterium tuberculosis complex (MTBC) in culture. We demonstrated the noninferiority of one commercial MTP64 ICT, the MGIT TBc identification (TBcID) test, to GenoType line probe assays for MTBC identification in positive MGIT cultures. Meta-analysis of MPT64 ICT performance for identification of MTBC in liquid culture confirmed similar very high sensitivities and specificities for all three commercial MPT64 assays for which sufficient data were available.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.05995-11

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