Mycobacterium tuberculosis Can Utilize Heme as an Iron Source-Reference-Cited by-同舟云学术

Mycobacterium tuberculosis Can Utilize Heme as an Iron Source

Published:2011-04 Issue:7 Volume:193 Page:1767-1770
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Jones Christopher M.¹,Niederweis Michael¹

Affiliation:

1. Department of Microbiology, University of Alabama at Birmingham, 609 Bevill Biomedical Research Building, 845 19th Street South, Birmingham, Alabama 35294

Abstract

ABSTRACT Most iron in mammals is found within the heme prosthetic group. Consequently, many bacterial pathogens possess heme acquisition systems to utilize iron from the host. Here, we demonstrate that Mycobacterium tuberculosis can utilize heme as an iron source, suggesting that M. tuberculosis possesses a yet-unknown heme acquisition system.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.01312-10

Reference33 articles.

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