New Technique (the NOW Test) for Rapid Detection of Streptococcus pneumoniae in the Nasopharynx

Author:

Faden Howard1,Heimerl Michael1,Goodman Gail1,Winkelstein Peter1,Varma Chelikani1

Affiliation:

1. Department of Pediatrics, State University of New York, University of Buffalo, and Children's Hospital of Buffalo, Buffalo, New York

Abstract

ABSTRACT Although the NOW test was originally introduced as a rapid pneumococcal antigen detection test for use with urine samples, it was successfully adapted to nasopharyngeal samples in the present study. The sensitivity, specificity, positive predictive value, and negative predictive value of the test were 92.2, 97.7, 95.9, and 95.5%, respectively. These results demonstrate that nasopharyngeal colonization with Streptococcus pneumoniae can be documented within 15 min of sample collection.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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