Reduction of Contamination of Mycobacterial Growth Indicator Tubes with a Modified Antimicrobial Combination

Author:

Chang Chulhun Ludgerus1,Park Tae Sung1,Oh Seung Hwan1,Kim Hyung Hoi1,Lee Eun Yup1,Son Han Chul1,Kim Cheol Min2

Affiliation:

1. Departments of Clinical Pathology

2. Biochemistry, College of Medicine, Pusan National University, Pusan, Korea

Abstract

ABSTRACT Culture in the fluorimetric Mycobacteria Growth Indicator Tube (MGIT) treated with a combination of vancomycin, amphotericin B, and nalidixic acid (VAN) showed growth of most strains of 31 mycobacterial species with a less-than-1-day delay. The results were similar to those in the MGIT with polymyxin B, amphotericin B, nalidixic acid, trimethoprim, and azlocillin, but with respiratory specimens, the MGIT with VAN showed a lower contamination rate with no change in the detection rate or time.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference21 articles.

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