Association of cagA and vacA Genotypes of Helicobacter pylori with Gastric Diseases in Estonia-Reference-Cited by-同舟云学术

Association of cagA and vacA Genotypes of Helicobacter pylori with Gastric Diseases in Estonia

Published:2002-01 Issue:1 Volume:40 Page:298-300
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Andreson Helena¹,Lõivukene Krista¹,Sillakivi Toomas²,Maaroos Heidi-Ingrid³,Ustav Mart⁴,Peetsalu Ants²,Mikelsaar Marika¹

Affiliation:

1. Department of Microbiology

2. Department of Surgery

3. Department of Polyclinic and Family Medicine

4. Institute of Molecular and Cell Biology, University of Tartu, Tartu 50411, Estonia

Abstract

ABSTRACT Gastric biopsy specimens from 156 adult patients from southern Estonia suffering from chronic gastritis, peptic ulcer disease, and perforated peptic ulcer were analyzed by PCR. The cagA gene was evenly distributed throughout 87% of the specimens from the patients with the different gastric diseases. The presence of the cagA gene correlated with that of vacA signal sequence type s1a (99%). However, no clear differences were found in the distribution of cagA and vacA genotypes among patients in Estonia with severe perforated peptic ulcer, uncomplicated peptic ulcer, or chronic gastritis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.40.1.298-300.2002

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