Longitudinal Quantitative Detection by Real-Time PCR of Mycoplasma genitalium in First-Pass Urine of Men with Recurrent Nongonococcal Urethritis

Author:

Deguchi Takashi1,Yoshida Takashi2,Yokoi Shigeaki1,Ito Masayasu1,Tamaki Masayoshi3,Ishiko Hiroaki2,Maeda Shin-Ichi3

Affiliation:

1. Department of Urology, Gifu University School of Medicine, Gifu 500-8705

2. Research and Development Department, Mitsubishi Kagaku Bio-Clinical Laboratories, Inc., Tokyo 174-8555

3. Department of Urology, Toyota Memorial Hospital, Toyota 471-8513, Japan

Abstract

ABSTRACT By using a TaqMan assay we monitored longitudinal changes in Mycoplasma genitalium loads in five men with recurrent M. genitalium -positive nongonococcal urethritis. We observed regrowth of M. genitalium persisting in hosts after treatment and a possible association of the increase in the M. genitalium load with emergence of symptoms and signs of nongonococcal urethritis in four of these patients.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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