Antimicrobial Agents from Marine Algae-Reference-Cited by-同舟云学术

Antimicrobial Agents from Marine Algae

Published:1975-03 Issue:3 Volume:7 Page:320-321
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Sims James J.¹,Donnell Mark S.¹,Leary John V.¹,Lacy George H.¹

Affiliation:

1. Department of Plant Pathology, University of California, Riverside, California 92502

Abstract

The antimicrobial activity of five compounds extracted from marine algae was tested against Staphylococcus aureus, Salmonella choleraesuis, Mycobacterium smegmatis, Candida albicans , and Escherichia coli . Three of the compounds, cycloeudesmol, laurinterol, and debromolaurinterol, exhibited activity at concentrations approaching that of streptomycin. None of the compounds inhibited all of the organisms tested. There appeared to be selectivity for gram-positive microbes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.7.3.320

Reference11 articles.

1. Baslow M. H. 1969. Marine pharmacology. The Williams & Wilkins Co. Baltimore.

2. Chisters C. G. C. and J. A. Stott. 1956. The production of antibiotic substances by seaweeds p. 49. In Proc. 2nd Int. Seaweed Symp. Pergamon Press New York.

3. Fenical W. and J. J. Sims. 1974. Cycloeudesmol an antibiotic cyclopropane containing sesquiterpene from the marine alga Chondria oppositiclada Dawson. Tetrahedron Lett. p. 1137-1140.

4. Fenical W. J. Sims. and P. Radlick. 1973. Chondriol a halogenated acetylene from the marine alga Chondria oppositiclada. Tetrahedron Lett. p. 313-316.

5. Irie T. M. Suzuki. E. Kurosawa and T. Masamune. 1966. Laurinterol and debromolaurinterol constituents from Laurencia intermedia. Tetrahedron Lett. p. 1837-1840.

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