Detection and Characterization of VIM-52, a New Variant of VIM-1 from a Klebsiella pneumoniae Clinical Isolate-Reference-Cited by-同舟云学术

Detection and Characterization of VIM-52, a New Variant of VIM-1 from a Klebsiella pneumoniae Clinical Isolate

Published:2021-10-18 Issue:11 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

de Barsy Marie¹,Mercuri Paola Sandra²,Oueslati Saoussen³⁴⁵,Elisée Eddy⁶,Huang Te-Din¹,Sacré Pierre¹,Iorga Bogdan I.⁶,Naas Thierry³⁴⁵^ORCID,Galleni Moreno²,Bogaerts Pierre¹^ORCID

Affiliation:

1. Laboratory of Bacteriology, CHU UCL Namur, Université Catholique de Louvain, Yvoir, Belgium

2. InBios-Laboratoire de Macromolécules Biologiques, Centre d'Ingénierie des Protéines, Université de Liège, Liège, Belgium

3. Team ReSIST, INSERM U1184, School of Medicine Université Paris-Saclay, LabEx LERMIT, Le Kremlin-Bicêtre, France

4. Bacteriology-Hygiene unit and French National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacteriaceae, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France

5. Evolution and Ecology of Resistance to Antibiotics Unit, Institut Pasteur—APHP-Université Paris-Sud, Paris, France

6. Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, Gif-sur-Yvette, France

Abstract

Over the last two decades, antimicrobial resistance has become a global health problem. In Gram-negative bacteria, metallo-β-lactamases (MBLs), which inactivate virtually all β-lactams, increasingly contribute to this phenomenon.

Funder

Belgian federal public service health, Food Chain Safety and Environment

Agence Nationale de la Recherche

Fonds De La Recherche Scientifique - FNRS

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02660-20

Reference40 articles.

1. Global antimicrobial resistance in Gram-negative pathogens and clinical need