Affiliation:
1. Northern Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, Peoria, Illinois 61604
Abstract
Mass spectral analysis of T-2 toxin formed during the growth of
Fusarium sporotrichioides
(ATCC 24043) in the presence of H
2
18
O showed incorporation of up to three
18
O atoms per toxin molecule. The carbonyl oxygens of the acetates at C-4 and C-15 and of the isovalerate at C-8 were derived from H
2
O. Toxin formed in the presence of
18
O molecular oxygen incorporated up to six
18
O atoms per toxin molecule. The overall incorporation was 78 and 92% of toxin molecules labeled for H
2
18
O and
18
O
2
labeled samples, respectively. The oxygens of position 1, the 12,13-epoxide, and the hydroxyl groups at C-3, C-4, C-8, and C-15 were all derived from molecular oxygen.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
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