Potency of Olorofim (F901318) Compared to Contemporary Antifungal Agents against Clinical Aspergillus fumigatus Isolates and Review of Azole Resistance Phenotype and Genotype Epidemiology in China-Reference-Cited by-同舟云学术

Potency of Olorofim (F901318) Compared to Contemporary Antifungal Agents against Clinical Aspergillus fumigatus Isolates and Review of Azole Resistance Phenotype and Genotype Epidemiology in China

Published:2021-04-19 Issue:5 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Su Huilin¹²³,Zhu Min¹,Tsui Clement Kin-Ming⁴⁵⁶,van der Lee Henrich²,Tehupeiory-Kooreman Marlou²,Zoll Jan²,Engel Tobias²,Li Li¹,Zhu Junhao¹,Lu Zihan¹,Zhang Qiangqiang¹,Verweij Paul E.²⁷^ORCID,Deng Shuwen⁸^ORCID

Affiliation:

1. Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China

2. Department of Medical Microbiology and Center of Expertise in Mycology Radboudumc/CWZ, Radboud University Medical Center, Nijmegen, The Netherlands

3. Department of Dermatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

4. Department of Pathology, Sidra Medicine, Doha, Qatar

5. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

6. Division of Infectious Diseases, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

7. Center for Infectious Diseases Research, Diagnostics and Laboratory Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands

8. Department of Medical Microbiology, The People's Hospital of Suzhou New District, Suzhou, Jiangsu, China

Abstract

Triazole resistance in Aspergillus fumigatus is an increasing worldwide problem that causes major challenges in the management of aspergillosis. New antifungal drugs are needed, with novel targets, that are effective in triazole-resistant infection.

Funder

China Postdoctoral Science Foundation

Suzhou Health and Family Planning Commission

Suzhou National New & Hi-Tech Industrial Development Zone

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02546-20

Reference46 articles.