Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist-Reference-Cited by-同舟云学术

Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist

Published:2021-08-25 Issue:18 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Sperk Maike¹,Ambikan Anoop T.¹,Ray Shilpa¹,Singh Kamal²,Mikaeloff Flora¹,Diez Rafael Ceña³,Narayanan Ashwathy¹,Vesterbacka Jan³,Nowak Piotr³,Sönnerborg Anders¹³,Neogi Ujjwal¹⁴^ORCID

Affiliation:

1. Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institute, ANA Futura, Stockholm, Sweden

2. Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA, 65211, USA

3. Department of Medicine Huddinge, Division of Infectious Diseases, Karolinska Institute, Karolinska University Hospital, Huddinge, Stockholm, Sweden

4. Manipal Institute of Virology (MIV), Manipal Academy of Higher Education, Manipal, Karnataka, India

Abstract

HIV-1 elite controllers (EC) are a rare group among HIV-1-infected individuals who can naturally control viral replication for a prolonged period. Due to their heterogeneous nature, no universal mechanism could be attributed to the EC status; instead, several host and viral factors have been discussed as playing a role.

Funder

Vetenskapsrådet

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00479-21

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