Affiliation:
1. Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA
Abstract
ABSTRACT
For a number of years, sirtuin enzymes have been appreciated as effective “sensors” of the cellular environment to rapidly transmit information to diverse cellular pathways. Much effort was placed into exploring their roles in human cancers and aging. However, a growing body of literature brings these enzymes to the spotlight in the field of virology. Here, we discuss sirtuin functions in the context of viral infection, which provide regulatory points for therapeutic intervention against pathogens.
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
National Science Foundation
HHS | NIH | National Heart, Lung, and Blood Institute
HHS | NIH | National Institute of General Medical Sciences
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Cited by
51 articles.
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