Assessment of the potential of insecticides, emulsifiers, and solvent mixtures to enhance viral infection in cultured mammalian cells

Author:

Brookman D H,Chopra C,Ecobichon D J,Kang C Y,Ritter L,Thorsen J

Abstract

Various insecticides, solvents, emulsifiers, and mixtures thereof were tested to determine whether these compounds are capable of enhancing the sensitivity of cultured mammalian cells to infection with vesicular stomatitis virus. None of 42 compounds tested significantly enhanced the viral infection.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference6 articles.

1. Oligonucleotide finger prints of RNA species obtained from rhabdoviruses belonging to the vesicular stomatitis subgroup;Clewley J. P.;J. Virol.,1977

2. Lethal interaction of ubiquitous insecticide carriers with virus;Crocker J. F. S.;Science,1976

3. Emulsifiers that enhance susceptibility to virus infection: increased virus penetration and reduced interferon response;Lee S. H. S.;Appl. Environ. Microbiol.,1980

4. A compromised interferon response: an etiologic factor in Reye's Syndrome;Rozee K. R.;Can. Med. Assoc. J.,1982

5. Rozee K. R. S. H. S. Lee J. F. S. Crocker and S. H. Safe. 1977. Enhanced virus replication in mammalian cells exposed to commercial emulsifiers p. 561. In Proceedings of a symposium on fenitrothion: the long-term effects of its use in forest ecosystems. NRCC publication no. 16073.

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