Effect of glucose on isocitrate lyase in Phycomyces blakesleeanus

Author:

Rua J1,De Arriaga D1,Busto F1,Soler J1

Affiliation:

1. Departamento de Bioquímica y Biología Molecular, Universidad de León, Spain.

Abstract

Repression of the synthesis of isocitrate lyase by glucose and/or induction of the synthesis of isocitrate lyase by acetate in Phycomyces blakesleeanus were demonstrated. Both glycerol and ethanol failed to induce isocitrate lyase activity. Furthermore, glucose appeared to cause an in vivo catabolite inactivation of the derepressed enzyme. Isocitrate lyase was inactivated both reversibly and irreversibly by glucose.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference20 articles.

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5. Galland P. and E. D. Lipson. 1987. Light physiology of Phycomyces sporangiophores p. 49-92. In E. Cerda-Olmedo and E. D. Lipson (ed.) Phycomyces. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.

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