Abstract
Susceptibility and resistance to Trypanosoma rhodesiense infections in inbred and H-2 congenic strains of mice were studied. Mean survival times and patterns of parasitemia were examined. C3HeB/FeJ mice were highly susceptible; CBA/J, A/J, and BALB/cByJ mice displayed an intermediate level of susceptibility; whereas C57BL/10 mice were highly resistant. H-2 congenic strains with the BL/10 background resembled the BL/10 parental type, thereby suggesting that the major histocompatibility complex does not play a major role in regulating resistance and susceptibility to infection with T. rhodesiense.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference28 articles.
1. Histocompatibility-linked IR genes;Benacerraf B.;Science,1972
2. Regulation ofleishmania populations within the host. HI. Genetic control of acute susceptibility of mice to Leishmania donovani infection;Bradley D. J.;Clin. Exp. Immunol.,1977
3. Regulation of Leishmania populations within the host. HI. Mapping of the locus controlling susceptibility to visceral leishmani in the mouse;Bradley D. J.;Clin. Exp. Immunol.,1979
4. Trypanosoma brucei: influence of host strain and parasite antigenic type on infections in mice;Clayton C. E.;Exp. Parasitol.,1978
5. The course of a Plasmodium berghei infection in six different mouse strains;Eling W.;Parasitenkunde,1977
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