Human Papillomavirus, Cytomegalovirus, and Adeno-Associated Virus Infections in Pregnant and Nonpregnant Women with Cervical Intraepithelial Neoplasia-Reference-Cited by-同舟云学术

Human Papillomavirus, Cytomegalovirus, and Adeno-Associated Virus Infections in Pregnant and Nonpregnant Women with Cervical Intraepithelial Neoplasia

Published:2004-03 Issue:3 Volume:42 Page:1341-1344
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Grce M.¹,Husnjak K.¹,Matovina M.¹,Milutin N.¹,Magdic L.²,Husnjak O.³,Pavelic K.¹

Affiliation:

1. Division of Molecular Medicine, Rudjer Boskovic Institute

2. Department of Obstetrics and Gynaecology, Medical School

3. Department of Physics, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia

Abstract

ABSTRACT Two hundred eight cervical specimens from two groups of subjects, 165 nonpregnant women and 53 pregnant women with cervical intraepithelial neoplasia (CIN) of grades I to III, were positive by PCR analyses for human papillomaviruses (HPVs), adeno-associated virus type 2 (AAV 2), and human cytomegalovirus (HCMV) in 67, 6, and 4.1% of the cases, respectively. The presence of AAV 2 infection was more frequently associated with pregnancy (17 versus 2.4%) and HPV-positive cervices (odds ratio = 6.358) than HCMV was. Increased HPV infection was strongly associated ( P < 0.001) with a higher CIN grade, but there is no evidence that AAV 2 and HCMV infections have any impact on CIN development.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.42.3.1341-1344.2004

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