Highly Conserved Alpha-Toxin Sequences of Avian Isolates of Clostridium perfringens-Reference-Cited by-同舟云学术

Highly Conserved Alpha-Toxin Sequences of Avian Isolates of Clostridium perfringens

Published:2004-03 Issue:3 Volume:42 Page:1345-1347
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Sheedy Scott A.¹²,Ingham Aaron B.¹,Rood Julian I.²,Moore Robert J.¹²

Affiliation:

1. Commonwealth Scientific and Industrial Research Organisation, Livestock Industries, Australian Animal Health Laboratory, Geelong 3220

2. Australian Research Council Centre for Structural and Functional Microbial Genomics, Department of Microbiology, Monash University, Geelong 3800, Australia

Abstract

ABSTRACT Clostridium perfringens causes necrotic enteritis in chickens, and alpha-toxin has been suggested to be a key virulence determinant. Analysis of the alpha-toxin of 25 chicken-derived C. perfringens strains demonstrated high homology to mammal-derived strains rather than to the only avian-derived C. perfringens alpha-toxin sequence reported previously.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.42.3.1345-1347.2003

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