Author:
Fauchet Floris,Treluyer Jean-Marc,Préta Laure-Helene,Valade Elodie,Pannier Emmanuelle,Urien Saik,Hirt Déborah
Abstract
ABSTRACTFor the first time, a population approach was used to describe abacavir (ABC) pharmacokinetics in HIV-infected pregnant and nonpregnant women. A total of 266 samples from 150 women were obtained. No covariate effect (from age, body weight, pregnancy, or gestational age) on ABC pharmacokinetics was found. Thus, it seems unnecessary to adapt the ABC dosing regimen during pregnancy.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
9 articles.
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