Consecutive Antibiotic Shortages Highlight Discrepancies between Microbiology and Prescribing Practices for Intra-abdominal Infections

Author:

Park Stacy C.1ORCID,Gillis-Crouch Grace R.1,Cox Heather L.2,Donohue Lindsay2,Morse Rena3,Vegesana Kasi3,Mathers Amy J.14

Affiliation:

1. Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA

2. Department of Pharmacy Services, University of Virginia Health System, Charlottesville, Virginia, USA

3. Health Information & Technology, University of Virginia Health System, Charlottesville, Virginia, USA

4. Clinical Microbiology Laboratory, Department of Pathology, University of Virginia Health System, Charlottesville, Virginia, USA

Abstract

Piperacillin-tazobactam (TZP) is frequently used for intra-abdominal infection (IAI). Our institution experienced consecutive shortages of TZP and cefepime, providing an opportunity to review prescribing patterns and microbiology for IAI.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference25 articles.

1. Cogan D, Karrar K, Iyer JK. 2018. Shortages, stockouts and scarcity. Access to Medicine Foundation, Amsterdam, The Netherlands.

2. Food and Drug Administration. 2011. A review of FDA’s approach to medical drug shortages.

3. The Impact of Anti-infective Drug Shortages on Hospitals in the United States: Trends and Causes

4. Antimicrobial Agent Shortages: The New Norm for Infectious Diseases Physicians

5. Impact of piperacillin-tazobactam shortage on meropenem use: implications for antimicrobial stewardship programs

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