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Do Nonsteroidal Anti-Inflammatory or COX-2 Inhibitor Drugs Increase the Nonunion or Delayed Union Rates After Fracture Surgery?

  • Published:2021-06-08 Issue:15 Volume:103 Page:1402-1410
  • ISSN:0021-9355
  • Container-title:Journal of Bone and Joint Surgery
  • language:en
  • Short-container-title:

Author:

Kim Hyojune,Kim Do-Hoon,Kim Dong Min,Kholinne Erica,Lee Eui-Sup,Alzahrani Wael Mohammed,Kim Ji Wan,Jeon In-Ho,Koh Kyoung Hwan

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Orthopedics and Sports Medicine,General Medicine,Surgery

Reference22 articles.

1. Epidemiology of fracture nonunion in 18 human bones;Zura;JAMA Surg.,2016

2. Risk of nonunion with nonselective NSAIDs, COX-2 inhibitors, and opioids;George;J Bone Joint Surg Am.,2020

3. Cyclooxygenase-2 inhibitors in human skeletal fracture healing;Daluiski;Orthopedics.,2006

4. Selective and nonselective cyclooxygenase-2 inhibitors and experimental fracture-healing. Reversibility of effects after short-term treatment;Gerstenfeld;J Bone Joint Surg Am.,2007

5. Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis?;Murnaghan;J Bone Joint Surg Am.,2006
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