IgG4-Related Spinal Hypertrophic Pachymeningitis With Neurological Deficit-Reference-Cited by-同舟云学术

IgG4-Related Spinal Hypertrophic Pachymeningitis With Neurological Deficit

Published:2023 Issue:2 Volume:13 Page:
ISSN:2160-3251
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language:en
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Author:

Tanaviriyachai Terdpong¹^ORCID,Chinvattanachot Guntarat¹^ORCID,Piyapromdee Urawit¹^ORCID,Sirisanthiti Piyaporn²^ORCID

Affiliation:

1. Department of Orthopedic Surgery, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand

2. Department of Hematology, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand

Abstract

Case: Immunoglobulin G4 (IgG4)-related spinal hypertrophic pachymeningitis (IgG4-RHP) is a rare disease characterized by diffuse inflammatory fibrosis of the spinal dura mater that can cause myelopathy and neurological deficits. Here, we report 2 cases in which both patients presented with myelopathy and paraplegia. They underwent decompressive laminectomy, and the diagnoses were confirmed through histopathologic examination. Both patients received prednisolone postoperatively, which was subsequently switched to methotrexate for maintenance. Conclusion: Two cases of IgG4-RHP were successfully treated with decompressive laminectomy and combined therapy with steroids and other immunosuppressive agents.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Orthopedics and Sports Medicine,Surgery

Reference17 articles.

1. Idiopathic hypertrophic craniocervical pachymeningitis;Zhu;Eur Spine J.,2015

2. A case of idiopathic hypertrophic pachymeningitis presenting with chronic headache and multiple cranial nerve palsies: a case report;Huang;Medicine (Baltimore).,2017

3. Idiopathic hypertrophic spinal pachymeningitis;Ranasinghe;J Neurosurg Spine.,2011

5. Idiopathic chronic hypertrophic craniocervical pachymeningitis: case report;Botella;Neurosurgery.,1994