Cryptococcal Osteomyelitis of the Patella-Reference-Cited by-同舟云学术

Cryptococcal Osteomyelitis of the Patella

Published:2024-07 Issue:3 Volume:14 Page:
ISSN:2160-3251
Container-title:JBJS Case Connector
language:en
Short-container-title:

Author:

Harper Jacob¹^ORCID,Weatherby Paul J.²^ORCID,Foreman Mark A.²

Affiliation:

1. John Sealy School of Medicine, The University of Texas Medical Branch, Galveston, Texas

2. Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch, Galveston, Texas

Abstract

Case: A 38-year-old woman presented to our clinic with right knee pain and difficulty ambulating. After cultures were obtained, a cryptococcal infection of the patella was identified. Subsequent workup revealed previously undiagnosed HIV/AIDS and a disseminated cryptococcal infection. Conclusion: Over a 20-month course, the patient was treated with fluconazole and antiretroviral therapy with very limited medication compliance. The disseminated infection caused cutaneous, hepatic, and cerebral complications. Eventually, compliance improved, and a final procedure to obtain post-treatment cultures and apply antifungal bone matrix was completed. The patient cleared the infection and will likely require lifetime antifungal treatment.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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