Zaburzenia neurorozwojowe – diagnostyka, obraz kliniczny i jego dynamika. Współczesne pytania i kierunki poszukiwań badawczych

Abstract

The article is an attempt to analyze the contemporary results of research on neurodevelopmental disorders in order to advance the search for various diagnostic approaches, predictors of a negative course of development, and changes in the dynamics of symptoms. The authors, based on a literature review, show that different levels of susceptibility to negative events are not a simple consequence of a specific NDD diagnosis [i.e., autism spectrum disorders (ASD) or ADHD] but also depend on the interaction of genetic factors (i.e., the general phenotype of NDD, which depends on spontaneous genetic mutations or changes in the number of copies of DNA fragments) and prenatal and perinatal environmental factors.