Intraspecific Diversity of <i>Mycobacterium abscessus</i> Isolated from Patients with Pulmonary Lesions-Reference-Cited by-同舟云学术

Intraspecific Diversity of <i>Mycobacterium abscessus</i> Isolated from Patients with Pulmonary Lesions

Published:2023-08-29 Issue:4 Volume:101 Page:40-45
ISSN:2542-1506
Container-title:Tuberculosis and Lung Diseases
language:
Short-container-title:Tuberk. bolezni lëgk.

Author:

Smirnova T. G.¹,Chernousova L. N.¹,Varlamov D. A.²,Sochivko D. G.²,Ergeshov A. E.³

Affiliation:

1. Central Tuberculosis Research Institute

2. All-Russia Research Institute of Agricultural Biotechnology

3. Central Tuberculosis Research Institute; A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Russian Ministry of Health

Abstract

The objective: to perform intraspecific differentiation of M. abscessus strains isolated from patients with pulmonary lesions using molecular genetic tests.Results. Intraspecific differentiation of 164 cultures of M. abscessus from 114 patients without cystic fibrosis showed that the subspecies M. abscessus subsp. dominated in the analysis set (90 of 114 patients; 78,95%), followed by M. abscessus subsp. massiliense (24/114; 21,05%). In 54 examined cystic fibrosis patients excreting non-tuberculous mycobacteria, M. abscessus was most often detected (41 patients out of 54; 75,93%). Intraspecific identification of the obtained M. abscessus isolates demonstrated the prevalence of the subspecies M. abscessus subsp. abscessus (29/41; 70,73%) over M. abscessus subsp. massiliense (11/41; 26,83%). In one case, a rare M. abscessus subsp. bolletii (1/41; 2,44%) was detected.

Publisher

LLC "Medical Knowledge and Technologies"

Subject

General Medicine

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