Management of Adverse Events during Treatment of Tuberculosis in the Patient with Systemic Lupus Erythematosus
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Published:2023-08-29
Issue:4
Volume:101
Page:80-86
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ISSN:2542-1506
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Container-title:Tuberculosis and Lung Diseases
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language:
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Short-container-title:Tuberk. bolezni lëgk.
Author:
Romanova M. I.1ORCID, Vaniev E. V.1ORCID, Churkin D. O.1ORCID, Abramchenko A. V.2ORCID, Gayda A. I.1ORCID, Lovacheva O. V.1ORCID, Samoylova A. G.1ORCID
Affiliation:
1. National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health 2. National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health; Pirogov Russian National Research Medical University, Russian Ministry of Health
Abstract
The article describes a clinical case of chemotherapy for drug susceptible rapidly progressive pulmonary tuberculosis in a patient with systemic lupus erythematosus taking glucocorticosteroids on regular basis. Due to adverse events that occurred when using the regimen of first line drugs, the patient discontinued taking first line drugs and was immediately switched to second line drugs. A timely decision to completely cancel the chemotherapy regimen with first line drugs that caused AE, the immediate start of the individual regimen (Bq, Lzd, Lfx, and Tzd) made it possible to cure pulmonary and bronchial tuberculosis in this patient. At the same time, data were obtained on the effective and safe use of tuberculosis treatment regimen (Bq, Lzd, Lfx, and Tzd) while taking GCS for SLE.
Publisher
LLC "Medical Knowledge and Technologies"
Reference11 articles.
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