Gut Microbiota and Pulmonary Tuberculosis (Literature Review)

Author:

Yukhimenko N. V.1ORCID,Sterlikova S. S.1ORCID,Gubkina M. F.2ORCID,Kayukova S. I.1ORCID

Affiliation:

1. Central Tuberculosis Research Institute

2. Central Tuberculosis Research Institute; Pirogov Russian National Research Medical University, Russian Ministry of Health

Abstract

The review analyzes 69 publications, of which 45 are devoted to studying gut microbiota in tuberculosis patients. The review presents data on the effect of gut microbiota disorders on the development of tuberculosis, severity and relapse rate. It covers the issues of changes in gut microbiota composition during anti-tuberculosis therapy and the effect of their management with probiotics on the tolerability of anti-tuberculosis therapy and effectiveness of treatment, including children.

Publisher

LLC "Medical Knowledge and Technologies"

Reference69 articles.

1. Adamova V., Gulyaeva N. Changes in microflora of the gut and upper respiratory tract in children with latent tuberculosis infection. FORCIPE, 2021, vol. 4, no. S1, pp. 921-921. (In Russ.)

2. Ardatskaya M.D., Belmer S.V., Dobritsa V.P., Zakharenko S.M., Lazebnik L.B., Minushkin O.N., Oreshko L.S., Sitkin S.I., Tkachenko E.I., Suvorov A.N., Khavkin A.I., Shenderov B.A. Intestinal dysbiosis (dysbacteriosis): current state of the problem, comprehensive diagnosis and management. Eksperimentalnaya i Klinicheskaya Gastroenterologiya, 2015, vol. 117, no. 5, pp. 13-50. (In Russ.)

3. Belova I.V., Soloviova I.V., Tochilina A.G., Barbolina S.F., Pavlunin A.V., Shprykov A.S. Efficiency of new immobilized probiotic as a part of treatment of pulmonary tuberculosis patients. Tuberculosis and Lung Diseases, 2017, vol. 95, no. 5, pp. 34-40. (In Russ.) https://doi.org/10.21292/2075-1230-2017-95-5-34-40

4. Vorobiov A.A., Bondarenko V.M., Lykova E.A., Grigoriev A.V., Matsulevich T.M. Microecological disorders in clinical pathology and their correction with bifid-containing probiotics. Vestnik RAMN, 2004, no. 2, pp. 13-17. (In Russ.)

5. Dugina N.I. Effektivnost kompleksnogo lecheniya bolnykh tuberkulezom organov dykhaniya v sochetanii s lekarstvenno-indutsirovannym disbakteriozom tolstoy kishki v usloviyakh spetsializirovannogo sanatoriya. Avtoref. diss. kand. med. nauk. [The effectiveness of comprehensive treatment of patients with respiratory tuberculosis and concurrent drug-induced colon dysbiosis in a specialized sanatorium: Synopsis of Doct. Diss.]. Moscow, 2005, 18 p.

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