EVALUATION OF THE BIOLOGICAL RELATIONSHIPS OF CORTICOSTERONE AND CORTISOL IN THE BODY OF CHICKENS DURING A STRESS REACTION

Abstract

The variability of corticosterone and cortisol concentrations and their ratio in laying hens during the development of a stress reaction, as well as the correlation of hormone levels with the variability of protein parameters in the blood, are evaluated. It was found that when the technological factor (the density of birds in the cage) changes by 1.5 times, the amount of glucocorticoids in the blood of birds during the stress reaction increases, both due to corticosterone and cortisol. Therefore, the balance between the hormones were not significantly changed and is in the range of 4.23-5,43conv. Units. When the technological factor is increased by 2 times, the content of corticosterone in the blood of birds mainly increases, determining an increase in the value of the corticosterone/cortisol ratio by 16.56-28.71%. The biological effects of glucocorticoids in the body of birds are realized by corticosterone, the level of which in a moderate and strong degree, including statistically significant, both under normal and stress conditions, is associated with the activity of transamination enzymes: Corticosterone-AlAT (r(group I) = 0,69±0,32 – 0,88±0,21; r(group II) =0.63±0.24 – 0.91±0.13; r(group III) = 0,59±0,22 – 0,76±0,16) and Corticosterone-AsAT (r(I group) = 0,57±0,36 – 0,83±0,25; r(group II) =0,68±0,23 – 0,72±0,22; r(group III) = 0,67±0,19 – 0,89±0,12), and also with the concentration of albumins during the development of a stress reaction (Corticosterone-Alb: r(group II) = -0,69±0,22 – -0,81±0,19; r(group III) = -0,58±0,21 – -0,81±0,16).