The aim of this experiment is to assess the potential of a plant extract to fight off Trypanosoma species, including Trypanosoma brucei brucei, Trypanosoma evansi, etc., by testing it at concentrations ranging from 006.25 to 400.00 mg/mL. The results obtained indicate that the plant extract may be a useful tool in the management of trypanosomiasis, but further studies are required to confirm its effectiveness.