Clinical case of primary multiple hemangioendothelioma in a child with CNS lesions-Reference-Cited by-同舟云学术

Clinical case of primary multiple hemangioendothelioma in a child with CNS lesions

Published:2023-02-03 Issue:4 Volume:9 Page:88-95
ISSN:2413-5496
Container-title:Russian Journal of Pediatric Hematology and Oncology
language:
Short-container-title:Ross. ž. det. gematol. onkol.

Author:

Kolcheva M. A.¹^ORCID,Kumirova E. V.²,Livshits M. I.³^ORCID,Skobeev D. A.³^ORCID,Umerenkov V. N.³^ORCID,Oleynikov B. I.¹^ORCID,Kuznetsova A. A.⁴^ORCID,Chmutin G. E.¹^ORCID

Affiliation:

1. Morozovskaya Children’s Clinical Hospital of the Moscow City Healthcare Department; Peoples’ Friendship University of Russia

2. Morozovskaya Children’s Clinical Hospital of the Moscow City Healthcare Department; Russian Scientific Center of Roentgenoradiology, Ministry of Health of Russia; N. N. Blokhin National Medical Research Centre of Oncology, Ministry of Health of Russia

3. Morozovskaya Children’s Clinical Hospital of the Moscow City Healthcare Department

4. Morozovskaya Children’s Clinical Hospital of the Moscow City Healthcare Department; Scientific and Practical Psychoneurological Center named after Z. P. Solovyov of the Moscow City Healthcare Department

Abstract

Epithelioid hemangioendothelioma (EHE) is one of the rarest vascular tumor found in the brain. In the pediatric group of patients, the proportion of EHE is only 0.02% of all brain neoplasms, and therefore oncogenesis and the causes are currently not well understood. Intracranial localization of EHE is extremely rare, nevertheless, this type of neoplasm should be included in the differential diagnostic series when multiple small intracerebral masses with hypointense MR signal in T2 mode are detected on magnetic resonance imaging. No specific therapy is currently developed for this disease, the optimal treatment is surgical removal of the volumetric mass if this type of treatment is possible. This article presents a clinical case of a primary multiple CNS lesion in a 14-year-old child with a long history of epilepsy. According to our data, the presented clinical case is the only one registered in the world, with primary multiple CNS EHE of the brain in the pediatric population

Publisher

OOO Grafika

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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