Atipical course of clostridial colitis in child with Hodgkin’s lymphoma-Reference-Cited by-同舟云学术

Atipical course of clostridial colitis in child with Hodgkin’s lymphoma

Published:2022-11-09 Issue:3 Volume:9 Page:107-112
ISSN:2413-5496
Container-title:Russian Journal of Pediatric Hematology and Oncology
language:
Short-container-title:Ross. ž. det. gematol. onkol.

Author:

Lyanguzov A. V.¹^ORCID,Ignatyev S. V.¹^ORCID,Kalinina S. L.¹^ORCID,Tselousova O. M.¹^ORCID,Tataurova I. P.¹^ORCID,Dyakonov D. A.¹^ORCID

Affiliation:

1. Kirov Research Institute of Hematology and Blood Transfusion under the Federal Medical Biological Agency

Abstract

The wide antibiotics use in different areas of medicine has significantly increased the incidence of pseudomembranous colitis caused by Clostridium difficile. Strong necessity of antibacterial therapy in hematological patients is the reason of a higher frequency of this complication after programmed chemotherapy and hematopoietic stem cell transplantation. The atypical course of clostridial colitis makes it difficult to diagnose, leads to delay of treatment and fatal complications. We presented the case of clostridial colitis with atypical clinical manifestations in the 8-year-old child with Hodgkin’s lymphoma. Disease was complicated by colon perforation and fecal peritonitis, which required surgery and long-term rehabilitation. The analysis of publications devoted to clostridial colitis in patients with hematological malignancies was carried out and possible reasons of its atypical course was reviewed. The ways to improve the diagnosis, treatment and prevention of this serious complication are presented.

Publisher

OOO Grafika

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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