Affiliation:
1. N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia
Abstract
The review article provides information about metastases of solid tumors in the lungs: from pathogenesis and the first experience of metastasectomy to a combined local method of therapeutic treatment. According to the literature, lung metastasectomy is part of the standard treatment for adults, but information about the surgical treatment of metastatic lesions in children remains poorly understood. As a rule, metastatic lesion accompanies the progression of the tumor process. Since the 1960s, methods of isolated lung perfusion have been developed, the results of which are reflected in a few articles, but most of the studies are aimed at exploring the possibilities of use and at the direct results of the implementation of this technique.
Subject
Oncology,Hematology,Pediatrics, Perinatology and Child Health
Reference43 articles.
1. 1 Shvarova A.V. Modern approaches to the treatment of high-risk soft tissue sarcomas in pediatric oncology. Detskaya onkologiya = Pediatric Oncology 2004;1:20–6. (In Russ.)
2. Kovalev V.I., Kovalev D.V., Nazhimov V.P., Myzin A.V., Zheludkova O.G., Netcvetaeva T.E., Strykov V.A., Polushkina O.B., Arkhipov A.N., Bogoroditckiy Yu.S. Analysis of results of surgical treatment of lung metastases of malignant tumors in children. Detskaya hirurgiya = Pediatric Surgery 2012;1:19–24. (In Russ.)
3. Kayton M.L. Pulmonary metastasectomy in pediatric patients. Thorac Surg Clin 2006;16:167–83. doi: 10.1016/j.thorsurg.2006.01.001.
4. Fidler I.J. The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited. Nature reviews. Cancer 2003;3:453–8. doi: 10.1038/nrc1098.
5. Paget S. The distribution of secondary growths in cancer of the breast. Cancer Metastasis Rev 1989;8:98–101. PMID: 2673568.