In vivolabel-free quantification of liver microcirculation using dual-modality microscopy

Author:

Yan Jie1,Kang Yuzhan2,Xu Shuoyu1,Ong Lee-Ling S.3,Zhuo Shuangmu4,Bunte Ralph M5,Chen Nanguang6,Asada H. Harry7,So Peter T. C.7,Wanless Ian R.8,Yu Hanry1

Affiliation:

1. BioSystems and Micromechanics IRG, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, #04-13/14 Enterprise Wing, 138602 Singapore, SingaporebInstitute of Bioengineering and Nanotechnology, 31 Biopolis Way, #04-01, 138669 Singapore, Singapor

2. BioSystems and Micromechanics IRG, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, #04-13/14 Enterprise Wing, 138602 Singapore, SingaporedZhujiang Hospital of Southern Medical University, Department of Critical Care Medicine, 253 Gongye

3. BioSystems and Micromechanics IRG, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, #04-13/14 Enterprise Wing, 138602 Singapore, Singapore

4. BioSystems and Micromechanics IRG, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, #04-13/14 Enterprise Wing, 138602 Singapore, SingaporeeFujian Normal University, Institute of Laser and Optoelectronics Technology, Fuzhou 350007, China

5. Duke-NUS Graduate Medical School Singapore, 8 College Road, 169857 Singapore, Singapore

6. National University of Singapore, Faculty of Engineering, Department of bioengineering, 9 Engineering Drive 1,117574 Singapore, Singapore

7. BioSystems and Micromechanics IRG, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, #04-13/14 Enterprise Wing, 138602 Singapore, SingaporehMassachusetts Institute of Technology, Department of Mechanical Engineering, 77 Massachusetts Avenu

8. Dalhousie University, Victoria General Hospital, Department of Pathology, Halifax, Nova Scotia, B3H 2Y9 Canada

Publisher

SPIE-Intl Soc Optical Eng

Subject

Biomedical Engineering,Atomic and Molecular Physics, and Optics,Biomaterials,Electronic, Optical and Magnetic Materials

Reference34 articles.

1. The pathogenesis of nonalcoholic steatohepatitis and other fatty liver diseases: a four-step model including the role of lipid release and hepatic venular obstruction in the progression to cirrhosis;Wanless,2004

2. Hepatic and portal vein thrombosis in cirrhosis: possible role in development of parenchymal extinction and portal hypertension;Wanless,1995

3. Cirrhosis reversal: a duel between dogma and myth

4. Colored microsphere technique as a new method for quantitative-multiple estimation of regional hepatic and portal blood flow

5. Liver blood flow measurement the interpretation of xenon133 clearance curves;Mackenzie,1976

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