Disrupting the p53-mdm2 interaction as a potential therapeutic modality
Author:
Publisher
Elsevier BV
Subject
Pharmacology (medical),Infectious Diseases,Cancer Research,Pharmacology,Oncology
Reference43 articles.
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3. The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation;Momand;Cell,1992
4. Mdm2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein;Chen;Mol Cell Biol,1996
5. The mdm2 oncogene can overcome wild-type p53 suppression of transformed cell growth;Finlay;Mol Cell Biol,1993
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