Comparative methods for the quantification of post-IMA myocardial damage

Abstract

This work aims to make a comparison between laboratory methods, especially by evaluating the role of troponin dosage and diagnostic imaging methods, specifically SPECT and cardiac magnetic resonance in the post-IMA evaluation. In both methods, we want to understand which one is able to be more predictive in terms of quantifying the extension of the infarcted area. Given the high sensitivity of troponin, even a very small damage can result from this examination, which SPECT or MRI cannot do. It must be said, however, that the initial high sensitivity troponin is not predictive of how much ischemic damage will be but is only useful for prognosis. The objective of the study was to determine the feasibility and diagnostic accuracy of an RMC stress protocol with the combined assessment of regional myocardial perfusion and contractility in the recognition of patients with significant coronary atherosclerotic disease leading to AMI, correlating the results with what would have been the study in SPECT.