Antitumor Effect of Methanolic Extract of Echinaceapurpureas leaves and Determination of Anti-microbialactivity of plant extract in vitro

Author:

Abd Algabar Fatima Amer,Mohsen Saja Mohammed,Mageed Ghanam Hissen

Abstract

The modern-day study objectives at assessing the in-vitro usage of extracts of Echinacea to evaluate their inhibitory effect on pathogenic microorganisms (7 species) were isolated from different environments The methanolic crude extract of leaves of Echinacea purpurea were prepared using soxhlet apparatus. These extracts were examined to inhibited microbial strains like Pseudomonas aeruginosa, S. aureus, Klebsiella pneumonia, E. coli, Streptococcus epidermidis, Aspergillus niger, and C. albicans using the disc diffusion method. Methanol extract is more effective against resistance zone 14 mm against streptococcus. Against the MCF7 cell line, this percentage was increased after 48 hours. To consider the cytotoxic properties of herbal extract alongside human breast cancer (MCF7) cell lines with a concentration range of Echinacea purpurea extracts (6.25,12.5, 25,50,100,400 g/ml). With the maximum percentage increase resistance (97%) observed in treatment with 400mg / ml against the MCF7 cell line. The lowest ratios were discussed with MCF7 having a permanent cure (20%) at 12.5 mg/ml. Finally, GC mass analysis was performed for crude extracts to identify the most active chemical compounds of Echinacea purpurea extract, resulting in the existence of 26 biologically dynamic composites, including nine composites with antioxidant and anticancer activity.

Publisher

EM International

Subject

Nature and Landscape Conservation,Ecology,Ecology, Evolution, Behavior and Systematics

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3