BIOLOGICAL ACTIVITY OF ESSENTIAL SAGE OIL
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Published:2022-03-30
Issue:1
Volume:22
Page:211-218
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ISSN:2068-3049
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Container-title:Journal of Science and Arts
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language:en
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Short-container-title:J. Sci. Arts
Author:
STANCIU GABRIELA1, LUPSOR SIMONA1, OANCEA ELENA2, MITITELU MAGDALENA3
Affiliation:
1. Ovidius University of Constanta, Department of Chemistry and Chemical Engineering, Constanta, Romania. 2. S.C.Dan-Elis.SRL, Product Manufacturing, 907285 Topraisar, Romania. 3. Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, 020956 Bucharest, Romania
Abstract
Essential sage oil (ESO) was isolated from dry leaves by steam distillation with Neo-Clevenger apparatus. The chemical analysis of the ESO consisted in the assessment of the total polyphenolic content (Folin-Ciocâlteu method) and of the radical scavenging activity with DPPH. The antioxidant activity was measured using two standard compounds: gallic acid and ascorbic acid. Phenolic content of essential oil of S. officinalis was significant (15.465 mg GAE/g oil) and antioxidant activity was high. Antibacterial activity of essential sage oil was evaluated against Gram positive and Gram-negative bacterial strains isolated from clinical specimens. The sage oil showed significant but variable antibacterial activity with inhibition zones ranging from 4 mm to 9.5.mm. The effect was stronger on Gram positive (Enterococcus, Staplylococcus) than Gram negative bacteria (Escherichia sp, Proteus sp, Klebsiella sp).
Publisher
Valahia University of Targoviste - Journal of Science and Arts
Subject
General Earth and Planetary Sciences,General Environmental Science
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