The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature
Author:
Rosso Claudio123, Morrey Mark E3, Schär Michael O3, Grezda Kushtrim124, _ _, _ _, Bouaicha Samy, Buess Eduard, Bühler Martin, Candrian Christian, Cikes Alec, Cunningham Gregory, Farron Alain, Flury Matthias, Hoffmeyer Pierre, Holzer Nicolas, Jost Bernhard, Lädermann Alexandre, Meyer Philipp, Müller Andreas Marc, Puskàs Gàbor, Riand Nicolas, Schneeberger Alberto, Simmen Beat, Schär Michael, Wieser Karl, Wirth Barbara, Zumstein Matthias
Affiliation:
1. ARTHRO Medics, Shoulder and Elbow Center, Basel, Switzerland 2. University of Basel, Basel, Switzerland 3. Swiss Orthopaedics, Grandvaux, Switzerland 4. Department of Orthopedic Surgery, Division of Shoulder and Elbow, Mayo Clinic, Rochester, Minnesota
Abstract
Platelet-rich plasma (PRP) is a revolutionary treatment that harnesses the regenerative power of the body's own platelets to promote healing and tissue regeneration.
While PRP therapy has emerged as a promising option for augmenting biologic healing in the shoulder, the complexity of shoulder disorders makes it difficult to draw definitive conclusions about the efficacy of PRP across different conditions and stages of disease.
Our comprehensive review of twenty-four studies highlights the current state of PRP therapy in shoulder pathologies, revealing a wide variety of number of patients, control groups and results. Despite these challenges, the regenerative potential of PRP therapy is moderate in some conditions, with numerous studies demonstrating the positive effects.
In conclusion, the authors of this study recommend the use of PRP therapy for adhesive capsulitis and rotator cuff repair of medium to large tears. However, they do not recommend the use of PRP for subacromial impingement or rotator cuff tears. It is up to the clinician's discretion to decide whether PRP therapy is appropriate for individual cases. However, there is still insufficient evidence to support the inclusion of PRP therapy in treatment protocols for other shoulder disorders. Therefore, further research is needed to fully explore the potential of PRP therapy in the treatment of various shoulder conditions.
Subject
Orthopedics and Sports Medicine,Surgery
Reference73 articles.
1. Platelets as key factors in inflammation: focus on CD40L/CD40;Cognasse,2022 2. Autologous platelet-rich plasma: a biological supplement to enhance adipose-derived mesenchymal stem cell expansion;Atashi,2015 3. The optimal platelet concentration in platelet-rich plasma for proliferation of human cells in vitro-diversity, biases, and possible basic experimental principles for further research in the field: a review;Straum,2020 4. Application of platelet-rich plasma to enhance tissue repair;Wroblewski,2010 5. Use of platelet rich plasma gel on wound healing: a systematic review and meta-analysis;Carter,2011
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|