Author:
Billig Håkan,Hedin Lars,Magnusson Claes
Abstract
Abstract. Oocyte-cumulus complexes and mural granulosa cells, respectively, isolated from pre-ovulatory rat follicles and cultured in lactate-free medium showed a continuous accumulation of lactate during a 1 to 7 h incubation. Lactate production was stimulated by gonadotrophins, both when administered in vivo and in vitro, with the exception that LH given in vivo did not affect granulosa cell lactate production. Since the oocyte is known to have specific demands on energy substrate, it is suggested that the lactate produced is important for the growing and maturing oocyte.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
32 articles.
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