Author:
Schleicher G.,Stumpf W. E.,Thiedemann K.-U.,Drews U.
Abstract
Abstract. Male, female and Tfm mice (testicular feminization) were injected with [3H]oestradiol or [3H]dihydrotestosterone, and autoradiograms prepared of male accessory sex organs and of the cervico-vaginal portion of the female reproductive tract.
After injection of [3H]oestradiol in male, female and Tfm animals a nuclear concentration of radioactivity was found in a subpopulation – about 20–30% – of the neurons of the genital ganglion. No such concentration was seen after [3H]dihydrotestosterone. The results suggest a direct genomic effect of oestradiol on certain neurons of the autonomic genital ganglion in both sexes.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
6 articles.
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