THE INFLUENCE OF VITAMIN C ON EOSINOPHIL RESPONSE TO ACUTE ALCOHOL INTOXICATION IN RATS

Author:

Vanha-Perttula T. P. J.

Abstract

ABSTRACT The effect of ethyl alcohol on the circulating eosinophil cells has been studied in female albino rats. An intoxicating dose of alcohol caused a marked depletion of circulating eosinophils which was most clearly evident four hours after the administration of the alcohol. The initial values were not reached before 24 hours had elapsed. Intraperitoneal injection of vitamin C 12 hours prior to the alcohol administration very effectively prevented this eosinopenic reaction. The mechanism of regulation of the eosinophil cells in the circulation has been discussed in the light of previous results and of those obtained in this study.

Publisher

Bioscientifica

Subject

Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Chemokines mediate ethanol-induced exacerbations of murine cockroach allergen asthma;Clinical and Experimental Immunology;2013-04-10

2. Ascorbic Acid, Alcohol, and Environmental Chemicals;Annals of the New York Academy of Sciences;1987-07

3. Ascorbic Acid and Elevated SGOT Levels after an Acute Dose of Ethanol in the Guinea Pig;Alcoholism: Clinical and Experimental Research;1987-06

4. Ascorbic acid and chronic alcohol consumption in the guinea pig;Toxicology and Applied Pharmacology;1986-06

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