URINARY TESTOSTERONE EXCRETION IN MEN IN NORMAL AND PATHOLOGICAL CONDITIONS

Abstract

ABSTRACT The excretion of testosterone in the urine of men has been studied using the method of Ismail & Harkness (1966 a); the estimates obtained with this procedure, which has satisfactory reliability criteria, agree with those from the majority of published methods. The effect of time, age, sexual activity, adrenal hyperfunction, hypopituitarism, undernutrition, precocious puberty, oligospermia and chlorpromazine administration have been investigated in a small number of subjects. All the above factors, except in the present case of oligospermia, are associated with alterations in testosterone excretion. The possible mechanisms and significance of these changes are discussed.