TESTICULAR GERMINAL DYSGENESIS (MALE TURNER'S SYNDROME)

Abstract

ABSTRACT A case of so-called male Turner's syndrome is reported in a 25 year old patient. Chromosomal studies revealed a normal male karyotype. The sex chromatin pattern was negative. Histological examination of the bilaterally cryptorchid testes showed a picture typical for intraabdominal testes. Analysis of the published cases of so-called male Turner's syndrome revealed uniform histological changes of the testis in the form of slight to moderate alterations of the tubular walls and absence or immaturity of the cells of the germinal epithelium. The clinical, histological and hormonal findings in this syndrome have been tentatively defined. The term testicular germinal dysgenesis is suggested as more appropriate for this syndrome than the commonly used name of male Turner's syndrome.