Abstract
ABSTRACT
Intravenous injection of 1.0 mg glucagon brings about a marked increase in the serum concentration of insulin in normal subjects. This increase sets in before the increase in blood sugar and reaches a peak 2–8 minutes after the injection.
Intravenous injection of 75 units secretin also results in a rapid increase in the serum concentration of insulin in normal subjects. This increase is less marked than that following glucagon and reaches its peak 3–4 minutes after the injection.
It must be assumed that glucagon as well as secretin contribute to the pronounced increase in insulin concentration during oral administration of glucose.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
37 articles.
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