PANCREATIC-GLUCAGON-LIKE IMMUNOREAGTIVITY AFTER INTRAVENOUS INSULIN IN NORMALS AND CHRONIC-PANCREATITIS PATIENTS

Abstract

Plasma glucose and pancreatic-glucagon-like immunoreactivity (GLI) were measured in normal subjects and in patients with chronic pancreatitis after an intravenous insulin injection. Both groups showed a fall of about 40 mg/100 ml in plasma glucose at from 0 to 30 minutes. In the normal group, the pancreatic GLI increased significantly above the 0-value at 30 and 60 minutes. No increase was observed in the pancreatitis patients. In all cases a decrease in gut GLI was observed during the test.