Abstract
ABSTRACT
The competitive protein binding technique for the measurement of progesterone has been further simplified for clinical use. Only 0.25 ml of plasma is needed for the determination during the luteal phase. One technician can assay 20 samples in one day with good precision and accuracy. The progesterone concentration in 20 normal human menstrual cycles was studied. During the follicular phase a mean concentration of 0.32 ± 0.25 (s) ng/ml plasma was found. At the mid-cycle peak of the total oestrogens the progesterone concentration started to rise and reached a plateau between 10–20 ng/ml 4 to 6 days later. From the plateau level, the concentration fell rapidly to less than 1 ng/ml at the onset of menstrual bleeding. The mean luteal phase lasted for 14.15 ± 1.05 (s) days.
Subject
Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism
Cited by
268 articles.
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